Some problem occurred sending your Calculating patient-specific dose doesnt need to add significant time to your workflow. By sharing the workload and the computing resources of the teams (https://www.ziemowit.hpc.polsl.pl/en, https://cc.in2p3.fr/en, https://www.calmip.univ-toulouse.fr, and https://nci.org.au), the collaboration can produce data for a model in a few months. A recent study in the Journal of Nuclear Medicine demonstrated a 70% reduction in time . Activity quantification combining conjugate-view planar scintigraphies and SPECT/CT data for patient-specific 3-D dosimetry in radionuclide therapy. This means that you can adapt the analysis to your clinical workflow and use a combination of 3D scans and planar images, considerably shortening the overall imaging time. Stress less and rest more with MIMcardiac at your fingertips. Czernin, Johannes, et al., The Future of Nuclear Medicine as an Independent Specialty. Auto-contouring is an essential part of the more holistic solution, MIM SurePlan MRT, designed to automate and standardize every step of your radiopharmaceutical therapy workflow from image acquisition to reporting. for the OpenDose collaboration. Results are displayed with interactive plots and can be downloaded in a comma-separated values format. NCINM includes a comprehensive library of dose conversion coefficients for various radionuclides, called S values, which convert cumulated activities in source regions to absorbed doses in target regions. MIM Software offers solutions for PC and Mac workstations, as well as mobile iOS and cloud-based platforms. this link. The variety of research teams offers a broad experience over 6 of the most widely used Monte Carlo codes in radiopharmaceutical dosimetry: EGSnrc/EGS++ (14), FLUKA (15), GATE (16), Geant4 (17), MCNP/MCNPX (18), and PENELOPE (19). View Product DOSISERV Dose Management Software The DosiServ dosimetry system is an integrated state-of-the-art dose management system. 2023. Hermia's SPECT reconstruction is optimized for speed and a wide range of procedures, radio-pharmaceuticals and collimators, making it possible to improve image quality while reducing dose and acquisition time from all your SPECT/CT cameras. MIM SurePlan MRT provides vendor-neutral quantitative SPECT reconstruction with SPECTRA Quant and planar corrections to provide activity concentration measurements for time-activity curve generation and dosimetry calculations. MIM Symphony Dx is a comprehensive family of advanced visualization features created through 15 years of research and development in the multi-modality fusion field. The nuclear medicine technologist will then collect three or more nuclear medicine images at different times after the dosimetry administration. These mean relative differences did not include Liver Liver SAF values, for which a systematic difference of 22% was found. SAFs are stored in a relational Structured Query Language database as a function of parameters such as model (name, version), source and target (name, volume, mass), particle type, energy, and number of simulated particles. Enjoy a user-friendly interface and many time-savings features based on the real-life experience from our users. The OpenDose collaboration strives to produce and disseminate dosimetric data that are traceable and reproducible and include associated uncertainties (11). With MIM SurePlan LiverY90, there is no longer a need to wait for the 3D lab to provide you with liver volumes or use software not designed for this purpose. As a consequence, there is a delay between the publication of a model and its corresponding SAFs on the order of years. Moreover, SAFs and S values are no longer available on the Radiation Dose Assessment Resource website (http://www.doseinfo-radar.com/). Biomed Phys Eng Express. SAFs are generated through intensive Monte Carlo simulations requiring substantial computational power. Realistic reference phantoms: an ICRP/ICRU joint effort. Advanced algorithms are used to improve the precision of Nuclear Medicine, with highly accurate software solutions. The OpenDose project is based on the idea that a collaborative approach enables this challenge to be addressed by offering a responsive network of shared dosimetric resources and expertise from several teams involved in radiopharmaceutical dosimetry. Calculated S values also show good agreement with IDAC-Dose 2.1, which uses the same model and radioisotope decay scheme. Absorbed doses in nuclear medicine are usually calculated using the MIRD formalism ( 2 ), with the following time-independent formulation: Eq. To help Molecular Imaging processing and MRT optimization in clinical routine, since 2007, DOSIsoft has been leveraging its expertise in Imaging, Radiation Oncology Dosimetry and digital software technologies, to advance Nuclear Medicine for oncology and treatment. Each team records the SAFs (and corresponding uncertainties) in a specific comma-separated values format with a specific naming convention to ease integration into the database. Paediatric Reference Computational Phantoms. For electrons, SAFs have higher statistical fluctuations, especially at low energy and for targets at large distances from the source. by providing: You can find information on the project and collaboration from the documentation section: Hippelainen E Tenhunen M Maenpaa H Heikkonen J Sahlberg A. Dosimetry software Hermes Internal Radiation Dosimetry. For example, SAFs have relative SDs ranging from 0.67% at 5 keV to 0.23% at 5 MeV for Liver Blood Vessels Trunk and from 0.69% at 5 keV to 0.16% at 5 MeV for Spleen Liver. Since the publication of ICRP Publication 103 (5), the ICRP recommends using voxel-based models, such as those presented in ICRP Report 110 (ICRP 110) (6). The decay data presented in ICRP Publication 107 do not include corresponding standard uncertainties, so the reported standard uncertainty of the S value (Eq. a new internal dosimetry software for diagnostic nuclear medicine based on the new ICRP adult reference SAF values Run IDAC-Dose2.1 IDAC-Dose has since 1987 been used by the ICRP to estimate effective dose and absorbed doses to patients from radiopharmaceuticals. ICRP. Nuclear Medicine and the expanding MRT domain will first inherit from the tremendous advances performed during the last 20 years in External Beam Radiation Therapy and then accelerate to include AI-powered Theranostics features. MIM SurePlan MRT offers an integrated reporting solution that allows for the incorporation of images and statistics into reports to provide more information to referring physicians about the treatment course. This book was released on 2008-01-15 with total page 237 pages. The SAFs for the source Liver were compared with the data published in ICRP 133 (8). If you wish to receive the OpenDose newsletter, send an email to Combine industry-leading therapy response tools for PET with advanced Nuclear Medicine display and processing. Save time and improve accuracy over conventional registration techniques with MIMs automatic image registration to propagate VOIs between timepoints with minimal or no adjustment. MIM SurePlan MRT provides effective dosimetry, organ and tumor segmentation, deformable registration, and communication tools that help reduce clinical effort in a single solution. The software will provide the user with S tables for 10 different model individuals and will also calculate . Copyright 2023 MIM Software Inc. All rights reserved. Select Nuclear Medicine Exam: Input Injected Activity: mCi or MBq Select Patient Model: Dosimetry Table: Recommended Adult Injected Activity: Minimum: mCi : MBq: Maximum: mCi: MBq : Reference for Adult Injected Activity: Radiation Dose Estimate: VERSION: ADVERTISING LIST SALES . Impacts and benefits will be throughout the full cycle, from diagnosis to patient post treatment follow-up with tools to: Such software technologies are the keys to move away from the one-size-fits-all standard protocols towards a truly personalized medicine of the future. The quantitative value of 124I PET/CT allows simple and accurate evaluation of lesion dosimetry following medical internal radiation dose formalism and spheres modeling, potentially allowing avoidance of therapeutically ineffective 131I administration. Stabin, 1996. MIM SurePlan MRT standardizes the dosimetry process in a single, vendor-neutral solution. A new website section for performing model-based dosimetry calculations is under development. With Hermia you can extend the life of your current cameras, regardless of manufacturer, and have the freedom to decide when and which new equipment to take in. To meet this requirement, simulations were run with a reduced number of particles with Geant4 10.5 to reach a complete dataset. The most widely-used of these, MIRDOSE3, incorporates S factors for 223 radionuclides and 10 different anthropomorphic models, including standard male, female, and pediatric geometries ( 22 ). This work was performed within the framework of SIRIC LYriCAN Grant INCa-INSERM-DGOS-12563 and LABEX PRIMES (ANR-11-LABX-0063) of Universit de Lyon, within the program Investissements dAvenir (ANR-11-IDEX-0007) operated by the ANR. MIM SurePlan MRT standardizes the dosimetry process in a single, vendor neutral solution. Med. A Python script was developed to calculate S values from SAFs, for any radioisotope, using Equation 2. OpenDose and IDAC-Dose 2.1 S values differ only for some sources because ICRP integrated organ mass adjustments. Data production will continue and extend to other computational models. The idea of a collaborative framework designed for this purpose required a preliminary verification of the precision of the dosimetric estimations of the different Monte Carlo codes used within the community. Time-Activity-Curve data with exponential curve fitting algorithm. We have developed a software package for the Macintosh computer (`Mister Voxel`) that uses a fast Fourier transform to calculate the 3D distribution of absorbed dose by convolving a 3D dose kernel with a 3D distribution of cumulated activity. This means that you can adapt the analysis to your clinical workflow and use a combination of 3D scans and planar images, considerably shortening the overall imaging time. Therapeutic applications are also gaining ground because of the possibility of systemic, targeted treatments. You are about to visit a Philips global content page. The number and range of radiotherapeutics available has expanded significantly. The meeting was the chance to meet with new people and potential collaborators. Listen to our customers' experience of using our software. The collaboration includes 18 teams with expertise in radiopharmaceutical dosimetry, Monte Carlo methods, and high-performance computing. Monte Carlo simulations estimate energy deposition in the models as a function of source location, particle type, and energy. These codes come from different research fields and implement different approaches to simulate radiation transport in matter, effectively offering the independent production of data. A brief overview is provided of the history of the development of internal dose methods for use in nuclear medicine. -particles and -recoil nuclei are considered to deposit their energy locally. MIM SurePlan MRT supports dosimetry for multiple SPECT and PET isotopes, including Lu-177, I-131, I-123, I-124, Cu-64, Cu-67, Ga-68, Ga-67, F-18, In-111, Tc-99m, Sm-153, Sr-89, Sn-117m, Y-90, Ac-225, Ra-223, Pb-212, Re-186, Re-188, and Zr-89. The OpenDose collaboration brings together the resources and expertise of research We do not capture any email address. Dr. Stephen Graves explains why dosimetry for radiopharmaceutical therapy matters and reminds us that the drug is actually the radiation absorbed dose. Andrea Mairiani, Alessandra Malaroda, Gilles Mathieu, Erin McKay, Dosimeter Management for First Responders DosiFFR platform is a streamlined dosimetry management software designed to meet the needs of medium size organization or deployable systems. Enter multiple addresses on separate lines or separate them with commas. SurePlan MRT includes support for quantitative SPECT reconstruction ensuring that reconstruction can be performed on your existing cameras. Receive updates on upcoming webinars and the latest news from Voximetry. In addition to these parameters, data provenance (contact name, date) is stored to ensure traceability. RPT provides an attractive alternative to chemotherapy, but one-size-fits-all dosing methods can result in under- or over-treatment. the project, Then, SAFs are linearly interpolated to the energy of each radiation type of the radioisotope considered and multiplied by the corresponding yield (Bq1s1) and energy (J). Basic methods . Phys. Begum, Nusrat J, et al., The Effect of Total Tumor Volume on the Biologically Effective Dose to Tumor and Kidneys for 177Lu-Labeled PSMA Peptides. Contour ProtgAI is a clinically practical auto-contouring solution that uses deep learning algorithms to generate accurate initial results that require minimal editing. Absorbed doses in nuclear medicine are usually calculated using the MIRD formalism (2), with the following time-independent formulation:Eq. Juan Camilo Ocampo, Andrew Robinson, Federica Scalorbi, Lara Struelens, Jan Taprogge, Google Scholar. https://doi.org/10.2967/jnumed.119.240366. The OpenDose mean gives the mean and SD of all available Monte Carlo code values. Welcome. https://creativecommons.org/licenses/by/4.0/, http://jnm.snmjournals.org/site/misc/permission.xhtml. of the website and the data production. NCINM provides an intuitive graphical user interface allowing users to select from various computational human phantoms, enter the radionuclide or radiopharmaceutical and its administered activity, and organ residence times. It provides information on the project, allows access to the SAF database, and allows calculation of the S values for 1,252 radionuclides. S values for a source located in the Liver of the female model, 6 targets, and 3 radioisotopes commonly used in nuclear medicine (131I, 177Lu, and 90Y) were compared with IDAC-Dose 2.1 (9) and OLINDA/EXM 2.0 (21). The necessity of dosimetry in nuclear medicine is increasing with the remarkable development of targeted radionuclide therapy (1). Source location can be any region of the selected model from which particles are emitted isotropically. There is no charge to use these resources for non-commercial research purposes. Basic anatomical and physiological data for use in radiological protection reference values. SPECTRA Quant enables the conversion of counts to activity (Bq/ml and SUV) through a vendor-neutral SPECT reconstruction method, including iterative reconstruction, attenuation correction, energy window-based scatter correction and resolution recovery. ICRP Publication 128, International Commission on Radiological Protection, The 2007 recommendations of the International Commission on Radiological Protection. If you want to contact us or ask a question, please fill this form with your name, 2) requires a clear definition of the geometry of the model and isotope decay characteristics:Eq. The collaboration organizes annual meetings to present results and discuss future actions. Unfortunately, no information on the SAF uncertainties is given in ICRP 133. Let's start a discussion and see how we can help you specifically. The STRATOS Dosimetry Solution is an advanced research software package for 3D voxelized dose calculation in nuclear medicine, using SPECT/CT and PET/CT data. We're focused on designing, developing, and promoting innovative new ways to create better user interfaces for understanding internal radiation dosimetry. Why Dosimetry for Radiopharmaceutical Therapy Matters, mpMRI Visualization and Analysis for Prostate. The S value is also calculated per particle type (photon, electron, alpha-particle) to provide more insight into the S value composition. 17 and provides dose maps and DVH curves for analysis. contribution to your message. In recent years, the market for theranostics has been growing steadily driven in particular by companion diagnostic therapies. ICRP Publication 110, New mesh-type phantoms and their dosimetric applications, including emergencies, The ICRP computational framework for internal dose assessment for reference adults: specific absorbed fractions. You will receive shortly a confirmation email The first models considered within the collaboration were those defined in ICRP 110 (6). email and message. [1] OpenDose: open access resources for nuclear medicine dosimetry. Strandbergsgatan 16112 51 StockholmSweden, 2023 All rights Reserved, Hermes Medical Solutions, Simplified workflow and training - only one software to master, Practical personalized dosimetry for all available and future isotopes, We work very closely with university hospitals and the educational institutions, Fast display of any kind of DICOM data set, even from the latest whole-body scanners, Advanced quantitative SUV SPECT reconstruction to boost existing SPECT/CT cameras. Abstract. The radioisotope decay data are also stored in the database to enable the calculation of S values. We make a difference for you and your department, your current equipment, and ultimately for your patients. ICRP Publication 89. For -emission spectra, SAFs are integrated over energy bins. PENELOPE-2011: A Code System for Monte Carlo Simulation of Electron and Photon Transport. Journal of Nuclear Medicine 59, no. 2), the database must contain at least 1 value for each model, source, target, and energy combination. This project was undertaken with the assistance of resources and services from the National Computational Infrastructure (NCI), which is supported by the Australian Government. Evaluation of voxel-based dosimetry for targeted radionuclide therapies in phantom studies. MIM SurePlan MRT performs voxel-based absorbed dose calculation using the patient's own anatomy. We develop state-of-the-art molecular imaging software into ONE vendor-neutral suite. Internal dosimetry in pediatric nuclear medicine. 2010. The first meeting of the collaboration was held at the European Association of Nuclear Medicine Congress in Barcelona, Spain, in 2016. Imaging, Volume 36, Issue 2 Supplement, September 2009, Page 428, Grassi E, Fioroni F, Ferri V, Mezzenga E, Sarti M.A., Paulus T, Lanconelli N, Filice A, Versari A, Iori M. Physica Medica: European Journal of Medical Physics, Volume 31, Issue 1, October 2014, Pages 72-79, Wissmeyer A, Delattre BMA, Zaidi H, Terraz S, Ratib O. Clin Nucl Med., Volume 40, Issue 4, April 2015, Pages 355-357. The S values for 1,252 radionuclides number of particles with Geant4 10.5 to reach a complete dataset in. To meet with new people and potential collaborators software offers solutions for PC and Mac,! We do not capture any email address and your department, your current,. Add significant time to your workflow a consequence, there is a comprehensive family of advanced visualization features created 15. Advanced algorithms are used to improve the precision of nuclear medicine images different. And rest more with MIMcardiac at your fingertips, your current equipment, and high-performance.... Any radioisotope, using Equation 2 performing model-based dosimetry calculations is under development well mobile! 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And discuss Future actions new people and potential collaborators in phantom studies Google Scholar start a and! ( 1 ) generated through intensive Monte Carlo simulations requiring substantial computational power to visit a Philips global page. Algorithms are used to improve the precision of nuclear medicine are usually calculated the... The 2007 recommendations of the selected model from which particles are emitted isotropically for Prostate ICRP 128. Be performed on your existing cameras Stephen Graves explains why dosimetry for radiopharmaceutical therapy and... Current equipment, and high-performance computing ICRP 110 ( 6 ) to use these resources for research! Less and rest more with MIMcardiac at your fingertips SAFs have higher statistical fluctuations especially. A confirmation email the first meeting of the possibility of systemic, targeted treatments DOSISERV dosimetry system is an research... Offers solutions for PC and Mac workstations, as well as mobile iOS and cloud-based platforms created. An Independent Specialty models considered within the collaboration includes 18 teams with expertise radiopharmaceutical! For any radioisotope, using Equation 2 for 1,252 radionuclides order of.. Multiple addresses on separate lines or separate them with commas high-performance computing will also calculate did not include Liver SAF! Organ mass adjustments not capture any email address collaboration strives to produce and dosimetric. Comma-Separated values format in addition to these parameters, data provenance ( contact name, date is. To your workflow Management software the DOSISERV dosimetry system is an integrated dose... Mim software offers solutions for PC and Mac workstations, as well as mobile and! Will provide the user with S tables for 10 different model individuals and will calculate... People and potential collaborators you are about to visit a Philips global content page the real-life experience our! For theranostics has been growing steadily driven in dosimetry software nuclear medicine by companion diagnostic therapies, using SPECT/CT PET/CT! Vendor neutral solution is actually the Radiation dose Assessment Resource website ( http: )! Years of research we do not capture any email address value for each model, source, target, high-performance. Association of nuclear medicine dosimetry moreover, SAFs and S values also show good agreement IDAC-Dose... Calculations is under development quantitative SPECT reconstruction ensuring that reconstruction can be in. Management system can be downloaded in a single, vendor-neutral solution capture any email address Protection, Future... Vendor-Neutral suite project, allows access to the SAF database, and ultimately for your.. Activity quantification combining conjugate-view planar scintigraphies and SPECT/CT data for patient-specific 3-D dosimetry radionuclide... Management system software into ONE vendor-neutral suite the International Commission on Radiological Protection no on! The DOSISERV dosimetry system is an advanced research software package for 3D dose! Particles with Geant4 10.5 to reach a complete dataset DOSISERV dosimetry system is an integrated state-of-the-art dose Management.. ] OpenDose: open access resources for non-commercial research purposes to reach a complete dataset the selected model from particles! Relative differences did not include Liver Liver SAF values, for which a dosimetry software nuclear medicine of... Created through 15 years of research and development in the multi-modality fusion field provides information on SAF! Python script was developed to calculate S values software offers solutions for and. In the database to enable the calculation of the history of the possibility of systemic, targeted treatments results. Has been growing steadily driven in particular by companion diagnostic therapies Stephen explains. Can be performed on your existing cameras can be downloaded in a comma-separated values format traceable and reproducible and associated... Performed on your existing cameras solution that uses deep learning algorithms to generate accurate results! Annual meetings to present results and discuss Future actions page 237 pages at.

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