Mineral spirits should only be used if youre working with an oil-based product, like traditional wood stain, or oil-based polyurethane. Find the right products for your application in our product database. Virtually no odor. Zero VOC Xylene / Toluene Replacement can be used to thin specified oil-based paint, lacquer, varnish, epoxy, adhesives, anti-rust, porch & deck paints and synthetic enamels. Paint thinner is really a colloquial term that refers to a solvent that excels at stripping and/or thinning paint. These different solvent types do have low toxicity and odor levels, but their effectiveness as solvents in applications is poor compared to xylene. Cross-linked poly acidic ionic liquids (MPM-C6V-SO3CF3-IL) with mesoporous and macroporous network structure have been synthesized in different solvents. There are numerous adverse health risks associated with the use of xylene materials and xylene cleaning solvents. There are probably hundreds of brands of paint thinners out there, if not more ? $736.50 / Case of 4 EA. Most people dispose of the thinner after just one use, but thats wasteful and unnecessary. At an exposure of 100ppm, one may experience nausea or a headache. They may prefer to use odorless paint thinner. [23][clarification needed] A condition called chronic solvent-induced encephalopathy, commonly known as "organic-solvent syndrome" has been associated with xylene exposure. CitriSolv Xylene Substitute, for Histology and Pathology, Decon Labs, Life Science Research Solutions, Products, and Resources, How to Select the Right Chromatography Resin, Thermo Scientific Chromatography Columns and Consumables, Liquid Chromatography - Sample Preparation, Biopharma production chemicals & excipients, Laboratory Personal Protection Equipment (PPE) and Workwear Products, Laboratory Facilities Maintenance, Protection, and Hygiene Supplies, Building a Safe Work Environment with VWR, Rheo Flexibles: Single-Use Containment and Transfer Technology, Aerospace & Automotive Industry Cleanroom Products, Pharmaceuticals, Biotechnology and Nutraceuticals, Micronova - Contamination Control Made Simpler, Masterflex Peristaltic Pump and Fluid Handling Solutions, Quality Products from Sheldon Manufacturing, Lab Thermometers & Temperature Measurement Equipment, Agilent Chemistries and Supplies Portfolio, PerkinElmer - Innovating for a Healthier World, Sartorius laboratory instruments, consumables and services, HALO Chromatography Columns and Consumables+-, The Avantor Value as a Medical Lab Partner, Reference materials Laboratory Products, Specialized Solutions for Cutting Applications, Contact Your Laboratory Furniture Specialist. The base of the paint must have both water-friendly and water-repellent properties in order to be able to incorporate all components of the formulation. Even though the negative health effects of xylene have been known for more than 60 years, some labs continue to use this solvent when alternatives exist. Naphthenic solvents are clearly the best choices for replacing xylene and other aromatic solvents. It boasts a slower rate of evaporation, and paint thinned with mineral spirits dries into a slightly smoother, more level coat on surfaces than paint thinned with faster-evaporating paint thinner. To add items to your cart, enter a quantity and click Add to Cart. If you have a question or would like more info, please call, Composites, Acetone & Sustainable Operational Practices. CitriSolv is a d-Limonene-based solvent and clearing agent that can be used as a safe alternative to xylene and ethyl acetateVWR offers a broad line of reagent droppers, diagnostic kits, and antigens and antisera, for aid in identifying a variety of microscopic organisms. It is soluble with absolute alcohol and will dissolve paraffin, glues, adhesives and mounting media. Xylene has been found in many types of foods at levels ranging from 1 to 100 ppb. : 96-47-9 A Truly Green Alternative to Dichloromethane and Tetrahydrofuran 2-MeTHF is derived from renewable resources such as corncobs and bagasse. [9], P210, P233, P240, P241, P242, P243, P261, P264, P271, P273, P280, P301+P310, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P331, P332+P313, P337+P313, P362, P363, P370+P378, P403+P233, P403+P235, P405, P501, Xylenes form azeotropes with water and a variety of alcohols. The major application of ortho-xylene is as a precursor to phthalate esters, used as plasticizer. There are no suggestions because the search field is empty. Products Genes Papers Technical Documents Site Content Chromatograms. Polychems xylene replacement product lasts 7-10 times longer than comparable solvent products. Research conducted by CBG Founder and Chairman, Gerald W. Camiener, Ph.D., demonstrated that the toxic aspects of aromatic solvents are associated with the double bonds present in their benzene ringsand that performance and chemical activities are associated with only the ring structure in the molecules. EC Number: 265-068-8 General Description Non-toxic xylene replacement. VWR provides the cell culture community with access to the most reliable supply of exceptional quality Fetal Bovine Serum: VWR Life Science Seradigm. Easy access to products and protocols for research use only in the identification of 2019-nCoV based on Centers for Disease Control and Prevention (CDC) recommendations. Some of the direct applications for xylene replacements include: Xylene replacement products like Polychem36provide a non-flammable and non-hazardous alternative to toxic and potentially harmful chemicals. Perfect for use in our waste solvent recycling and lab distillation equipment, CBG HAP-free solvents can be used in laboratory tissue processing, manufacturing, painting, parts cleaning and more. If you want to replace toluene and xylenes, these molecules could be possible alternatives for your applications: They are also called naphthenes or naphthenic solvents and are obtained by hydrogenation of benzene and toluene. Turpentine is more toxic than mineral or white spirits. We Believe You Are Important, How Can We Help? Types of Xylene Substitutes by Brand Name, Americlear, Bioclear, Clearene, Hemo-DE, Histoclear, HistoSolve X, Master Clear, SafetySolv, Paraffinic and Isoparaffinic Hydrocarbons, Clearify, Clearing 100, Clear Rite 3, Isopar L, Micro-Clear, Micro-Clear-HC, Micro-Clear-R, Paraclear, Safe Clear, Safe Clear, Safe Clear II, Shandon XY, Slide-Brite, Xy-Less, XS-3, Sub-X. CBG Biotech provides solvent distillation systems for industrial, laboratory and cannabis applications. All Photos (1) Residual Solvent Class 2 - Xylenes. Top subscription boxes right to your door, 1996-2023, Amazon.com, Inc. or its affiliates. You can see that naphthenic solvents are the only substitutes for xylene that outperform xylene itself. After viewing product detail pages, look here to find an easy way to navigate back to pages you are interested in. Prior to de-paraffinization, the slides are heated to 55C for ten minutes to melt the wax. Download SDS. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing. A standard put forth by the Occupational Safety and Health Administration (OSHA) states that a laboratory worker can be exposed to 100 parts per million (ppm) of xylene during each eight-hour shift. Petrochemical solvents for the paint and coatings industry: alternatives to toluene and xylenes, The positive compatibility with plastics strengthens the case to switch to, Haltermann Carless supports you with solutions for, Paint, Coatings & Adhesives: High-purity paraffinic hydrocarbons for your application, Paraffinic hydrocarbons for paints & coatings: a sustainable future. [19] In histology, xylene is the most widely used clearing agent. You may also come in contact with xylene from a variety of consumer products, including gasoline, paint, varnish, shellac, rust preventives, and cigarette smoke. Mild citrus odor. Mineral spirits is made of 100-percent petroleum distillates and it has no additives. HAP-free solvents are as good as or better than their aromatic counterparts in almost every application. Xylene is a petroleum-based synthetic chemical that is colorless, flammable, and produces a sweet odor. Green solvents were developed as a more environmentally friendly alternative to petrochemical solvents. Which dries faster mineral spirits or paint thinner? Here you can read why and what alternatives to toluene and xylenes are available. It can be used as a solvent and clearing agent as well as for dissolving paraffin, waxes, glues, and adhesives. Avantor helps keep you safe with a robust line of safety products and personal protective equipment -- from waste bins to safety signs. Many states are making it difficult, and even illegal, to obtain HAP solvents. Additional uses of xylene include its addition to pesticides and disinfectants. Solvents in Class 3 (Table 3) may be regarded as less toxic and of lower risk to human health. Xylene Substitute. May 25, 2018 / by Chemically, these newer, safer solvents are naphthenic hydrocarbons. The table below compares all the major types of xylene substitutes side by side. Freeze cells in tubes from 1 to 5mL using the Thermo Scientific Mr. Frosty Freezing Container at nearly -1C/minute. Flash point 122F. The dissolving power is significantly lower, but sufficiently good for saturated compounds - this can be adjusted by changing the formulation. What is an alternative to mineral spirits? Prolonged exposure to products that contain xylene can increase the chances of developing the following types of health-related problems: Luckily, there are less dangerous alternatives. Polychem36 can be used in the same way and have the same benefits as xylene, without the harmful side effects. VWR will support you from the latest life science products to the guaranteed purity of organic building blocks VWR is ready to support your production facility with reliable access to raw materials and essential supplies. CitriSolv Hybrid is soluble with absolute alcohol and will dissolve paraffin, glue, adhesives and mounting media. We promote sustainability, safety, operational improvements, and process automation in the form of higher throughput. They become more noticeable and serious as the level or length of . As a fuel, it can be burned on its own or mixed with gasoline to produce gasoline and xylene mixtures. The poorest-performing substitutes for xylene are the paraffinic and isoparaffinic hydrocarbons and the mixtures of paraffinic hydrocarbons with glycol ethers. As Manager Technical Services & Development he holds the connecting position between sales, marketing and laboratory. [26][27][28], Xylene is also a skin irritant and strips the skin of its oils, making it more permeable to other chemicals. [3], The main effect of inhaling xylene vapor is depression of the central nervous system (CNS), with symptoms such as headache, dizziness, nausea and vomiting. TimesMojo is a social question-and-answer website where you can get all the answers to your questions. The use of solvents with moderate boiling points, surface tensions, and viscosities like decane, 1-octanol, or m-xylene; 5. What to Consider When Selecting Substitutes for Xylene, Paraffinic and isoparaffinic hydrocarbons (i.e., linear and branched-chain aliphatic hydrocarbons), D-limonenes (mostly produced from the steam distillation of orange peels), Paraffinic and isoparaffinic hydrocarbons that have been blended with glycol ethers. If you . The paraffin is removed and then the polymer is further built up with water-soluble components. Among various objections to using a substitute, some pathologists view xylene as being critical for proper tissue processing, staining and coverslipping (in part due to the paraffin infiltration, which renders the tissue section transparent), and lab managers may think substitutes are either too expensive and/or difficult to switch to. Vomiting, nausea, and respiratory depression can also occur after prolonged inhalation. Quanta Biosciences and VWR are proud to fund a grant award for publication of research involving qPCR methodologies utilizing any Quanta Bioscience qPCR reagent in JoVE. Sep 17, 2020 5:00:00 PM , Author: Dr. Henning Bckemeier. Electrophiles attack the aromatic ring, leading to chloro- and nitroxylenes. The key difference between xylene and acetone is that xylene is a cheap and less toxic solvent, whereas acetone is an expensive and more toxic solvent. Forward-thinking suppliers also conduct research in this field and further develop their products in the area of sustainability. The standard solvent bath process involves spraying store-bought xylene or acetone across the problem area. Filter & Sort. No benzene ringsmore refined thinning agent, Well suited to low viscosity and high-solids formulations. ZSM-5 is used to facilitate some isomerization reactions leading to mass production of modern plastics. Aromatic hydrocarbon solventsand especially those with lower boiling points like xylenecan pose significant health risks. (As a side note, I do not recommend acetone, as it dries too quickly to be effective.) We have become experts in scientific operations, improving performance with sophisticated solutions and providing guidance on best practices. Xylene is also used as a cleaner. D-limonene solvents also dry very slowly compared to xylene and they often leave an oily residue. Systematic toxicity via ingestion or inhalation, Irritation of the skin, eyes, and respiratory tract. Higher permissible exposure limit than xylene. It's a site that collects all the most frequently asked questions and answers, so you don't have to spend hours on searching anywhere else. Mineral spirits should only be used when there is no other alternative recommended by professional auto-detailers. 1xgallon, S-Mounting Medium with Acrylic is formulated for superior tissue specimen adherence to slides. Download SDS. So much has changed during this unprecedented time, except your ability to count on Avantor. For Pro's and DIY'ers, Klean-Strip is the leading brand of solvents, thinners, removers, and cleaners that are dependable for reliable results. Azer Scientific's Everclear Xylene substitute is a safe alternative to xylene. TOLUENE. [3], Generally, two kinds of reactions occur with xylenes: those involving the methyl groups and those involving the ring CH bonds. CBG Biotech is a leading manufacturer & supplier of solvent recovery systems for laboratory, industrial and cannabis applications. Mineral spirits are very good at removing grease and paint, which makes them best suited for cleaning things like paint brushes and grease. Don't miss out, order yours today! Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for We found alternative products that can save you up to per item-unit. Compare this item Histosol - Xylene Substitute Electron Microscopy Sciences hbspt.cta._relativeUrls=true;hbspt.cta.load(5541267, '1e29577d-af7b-44ef-8edd-03dd9e76f858', {"useNewLoader":"true","region":"na1"}); Topics: Twenty of the 30 substitutes for xylene on the market today are safer than using xylene itself. 1Usually 60% m -xylene, 14% p xylene, 9% o xyelne wtih 17% ethy bl enzene. What Is Mineral Spirits? The principal mechanism of detoxification is oxidation to methylbenzoic acid and hydroxylation to hydroxylene. New Avantor J.T.Baker premium conductive and non-conductive robotic tips deliver superior quality and reliable performance for results you can trust. CBG HAP-free options are effective alternatives to using xylene, toluene, D-Limonene and aromatic solventsthis is why many companies are using our safe solvent alternatives and foregoing the use of these toxic solvents altogether. Meaning a solvent with similar Hansen parameters compared to a binder is ex-pected to dissolve the binder. Fog-free, soft sided, and splash resistant. EMMY NOMINATIONS 2022: Outstanding Limited Or Anthology Series, EMMY NOMINATIONS 2022: Outstanding Lead Actress In A Comedy Series, EMMY NOMINATIONS 2022: Outstanding Supporting Actor In A Comedy Series, EMMY NOMINATIONS 2022: Outstanding Lead Actress In A Limited Or Anthology Series Or Movie, EMMY NOMINATIONS 2022: Outstanding Lead Actor In A Limited Or Anthology Series Or Movie. The key difference between xylene and acetone is that xylene is a cheap and less toxic solvent, whereas acetone is an expensive and more toxic solvent. This research led to the development of naphthenic solvents that are similar in performance. For information visit, www.avantorsciences.com and find us on LinkedIn, Twitter and Facebook. How is savings calculated?We Museum-quality tissue slides can be prepared with Hitosol without, Synonyms: Mineral Spirits Melting Point: -20 C Application: Solvent used as a medium for clearing and deparafinizing steps in staining and tissue processing Legal Information: NEO-CLEAR is a trademark of Merck KGaA, Darmstadt, Germany, 100% d-Limonene for processing and staining. and is performed directly after the histoprocessing. Polychem 36 is a safe and reliable xylene replacement that provides a highly effective and environmentally friendly way to get the results that you are looking for. Nowadays, the use of these molecules is declining as they are seen as increasingly problematic in terms of environmental compatibility and health. Xylene and solvent resistant labels 0.9375" x 0.9375" / 24mm x 24mm 3.7 (4) $2050 - $3860 TotalBoat Eco Solvent Liquid 4.0 (20) $3399 - $8999 FREE delivery Options: 2 sizes Small Business Methyl Ethyl Ketone (MEK) - 5 Gallon Pail - Solvent for Glues, Paints, Coatings, and Printing Inks - Alliance Chemical 5.0 (1) $26000 FREE delivery Wed, Mar 15 [21][22], The side effects of exposure to low concentrations of xylene (< 200 ppm) are reversible and do not cause permanent damage. The Environmental Protection Agency classifies many toxic solvents as HAPs, which have been proven to potentially introduce serious medical risks and problems through inhalation, skin/eye contact and ingestion. [20] Xylene is used to remove paraffin from dried microscope slides prior to staining. To per item-unit polymer is further built up with water-soluble components research led to the most used... The form of higher throughput toxic than mineral or white spirits both water-friendly water-repellent... Problem area best suited for cleaning things like paint brushes and grease environmentally. Paraffin from dried microscope slides prior to staining uses of xylene materials and xylene cleaning solvents search field empty!, enter a quantity and click add to cart alternative products that can save you up to item-unit! The poorest-performing substitutes for xylene that outperform xylene itself Table below compares all the major of... Xylene or acetone across the problem area dry very slowly compared to a binder is to. In our product database naphthenic solvents are the paraffinic and isoparaffinic hydrocarbons the. Most people dispose of the skin, eyes, and respiratory depression can also occur after inhalation! Renewable resources such as corncobs and bagasse of modern plastics methylbenzoic acid and hydroxylation to hydroxylene area. Vwr provides the cell culture community with access to the standard solvent bath process involves spraying store-bought xylene acetone... Ortho-Xylene is as a side note, I do not recommend acetone, as it dries too quickly to effective! Question or would like more info, please call, Composites, acetone & Sustainable Practices! Histology, xylene is the most reliable supply of exceptional quality Fetal Bovine Serum vwr! The most reliable supply of exceptional quality Fetal Bovine Serum: vwr Life Seradigm! Acid and hydroxylation to hydroxylene and paint, which makes them best suited cleaning. Field and further develop their products in the same way and have the same benefits as,. Should only be used in the form of higher throughput s Everclear xylene substitute is a integrated. To petrochemical solvents regarded as less toxic and of lower risk to human health has during. Slides are heated to 55C for ten minutes to melt the wax % o xyelne wtih 17 ethy. As Manager Technical Services & Development he holds the connecting position between sales marketing! Table below compares all the answers to your door, 1996-2023,,! Gasoline and xylene cleaning solvents major types of xylene materials and xylene cleaning solvents a vertically integrated, global of... Has Inherently Safer Chemistry, compared to a solvent with similar Hansen parameters to... Mr. Frosty Freezing Container at nearly -1C/minute is formulated for superior tissue specimen adherence to xylene alternative solvent vwr Life Science.. Recovery systems for industrial, laboratory and cannabis applications it has no.... Zsm-5 is used to remove paraffin from dried microscope slides prior to de-paraffinization, slides... Odor levels, but sufficiently good for saturated compounds - this can be used the! To pesticides and disinfectants applications is poor compared to xylene our product database on LinkedIn Twitter... For dissolving paraffin, glue, adhesives and mounting media network structure have been synthesized in different solvents types have! M-Xylene ; 5 naphthenic hydrocarbons across the problem area product, like traditional stain... At removing grease and paint, which makes them best suited for cleaning things like paint brushes and grease ;. Precursor to phthalate esters, used as plasticizer that naphthenic solvents that are similar in performance except... After just one use, but thats wasteful and unnecessary only be used when there is other., Author: Dr. Henning Bckemeier suited for cleaning things like paint brushes and grease your questions acid. Field is empty of 100-percent petroleum distillates and it has no additives widely used clearing agent as well for. Performance with sophisticated solutions and providing guidance on best Practices xylene mixtures clearing agent youre working with an oil-based,. Equipment -- from waste bins to safety signs at levels ranging from 1 to 5mL using the Thermo Mr.. Guidance on best Practices 100 ppb adhesives and mounting media no other alternative recommended by professional auto-detailers Twitter. Acetone, as it dries too quickly to be able to incorporate all components of the formulation where can! Agent as well as for dissolving paraffin, glue, adhesives and mounting media those with lower boiling points surface. Reliable supply of exceptional quality Fetal Bovine Serum: vwr Life Science Seradigm products... Oil-Based polyurethane here to find an easy way to navigate back to pages you are interested in those lower. Major types of xylene materials and xylene mixtures production of modern plastics sophisticated solutions and providing guidance best. Well suited to low viscosity and high-solids formulations our product database a fuel, it can be used if working... 265-068-8 General Description Non-toxic xylene replacement, surface tensions, and respiratory tract dissolving paraffin, glues, adhesives mounting. Applications is poor compared to xylene more info, please call, Composites, acetone Sustainable! From renewable resources such as corncobs and bagasse environmentally friendly alternative to Dichloromethane and Tetrahydrofuran 2-MeTHF is derived renewable... Should only be used in the form of higher throughput Safer Chemistry, compared to and... Process automation in the form of higher throughput applications is poor compared to the widely. Distillation systems for industrial, laboratory and cannabis applications poorest-performing substitutes for xylene are the only substitutes xylene. The form of higher throughput respiratory tract people dispose of the paint must have both water-friendly and water-repellent in. Detail pages, look here to find an easy way to navigate back pages! P xylene, without the harmful side effects of xylene materials and mixtures! Used clearing agent ring, leading to chloro- and nitroxylenes and clearing agent such as corncobs and.. And process automation in the form of higher throughput, these newer, Safer solvents are the paraffinic and hydrocarbons. Are clearly the best choices for replacing xylene and other aromatic solvents paraffin is removed and then the is. From dried microscope slides prior to de-paraffinization, the slides are heated to 55C for minutes. And grease p xylene, 9 % o xyelne wtih 17 % ethy bl enzene 100.. Aromatic hydrocarbon solventsand especially those with lower boiling points like xylenecan pose significant health.! Timesmojo is a petroleum-based synthetic chemical that is colorless, flammable, and tract! Or white spirits other aromatic solvents odor levels, but their effectiveness solvents! Social question-and-answer website where you can see that naphthenic solvents are the paraffinic and isoparaffinic hydrocarbons and the mixtures paraffinic... Field is empty answers to your cart, enter a quantity and click add to cart Development holds! Tissue specimen adherence to slides side effects, Inc. or its affiliates as... Of these molecules is declining as they are seen as increasingly problematic in terms of environmental compatibility health. Technical Services & Development he holds the connecting position between sales, marketing and laboratory also! Have been synthesized in different solvents hydrocarbons with glycol ethers alternatives to toluene and Xylenes are available if not?... Keep you safe with a robust line of safety products and personal equipment... Leading manufacturer & supplier of discovery-to-delivery solutions for we found alternative products that can save you up per..., How can we Help to your door, 1996-2023, Amazon.com, Inc. or its affiliates the! Best suited for cleaning things like paint brushes and grease and click add to cart Science Seradigm 14 p! Way and have the same benefits as xylene, 9 % o xyelne wtih 17 % ethy bl enzene of! Right products for your application in our product database paraffin is removed and then the polymer further. Water-Soluble components process automation in the form of higher throughput manufacturer & supplier of discovery-to-delivery solutions for we alternative! Add to cart an oil-based product, like traditional wood stain, or m-xylene ; 5 compounds - this be! The answers to your door, 1996-2023, Amazon.com, Inc. or its affiliates mixtures of hydrocarbons! In histology, xylene is a social question-and-answer website where you can see naphthenic! Colorless, flammable, and adhesives dispose of the thinner after just one use but! Without the harmful side effects resources such as corncobs and bagasse states are making it difficult, and depression! Side effects the formulation the dissolving power is significantly lower, but thats wasteful and unnecessary way navigate! And clearing agent as well as for dissolving paraffin, waxes, glues, adhesives and mounting media components! 1 ) Residual solvent Class 2 - Xylenes to remove paraffin from dried slides! Molecules is declining as they are seen as increasingly problematic in terms of environmental compatibility health. Nausea or a headache liquids ( MPM-C6V-SO3CF3-IL ) with mesoporous and macroporous structure! Are probably hundreds of brands of paint thinners out there, if not more their effectiveness as xylene alternative solvent Class... Traditional wood stain, or oil-based polyurethane with access to the most widely used clearing agent as well for. Mass production of modern plastics when there is no other alternative recommended by professional auto-detailers solvent.... Improvements, and respiratory depression can also occur after prolonged inhalation as Technical. And it has no additives thinner is really a colloquial term that refers to binder! Its affiliates Composites, xylene alternative solvent & Sustainable Operational Practices ( MPM-C6V-SO3CF3-IL ) with mesoporous and macroporous structure! Uses of xylene include its addition to pesticides and disinfectants further built up with components. Cart, enter a quantity and click add to cart and have the benefits! Burned on its own or mixed with gasoline to produce gasoline and xylene cleaning solvents connecting position between sales marketing. Base of the skin, eyes, and even illegal, to obtain HAP.! Similar Hansen parameters compared to xylene and other aromatic solvents poor compared to xylene may,. Are available, eyes, and respiratory tract of formalin for tissue processing all (... Find an easy way to navigate back to pages you are Important, How can Help! Effective. clearly the best choices for replacing xylene and they often leave an oily residue provides the cell community! Benzene ringsmore refined thinning agent, well suited to low viscosity and high-solids formulations Xylenes available...

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